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Page 1
Structural mechanism for the selective phosphorylation of DNA-loaded MCM double hexamers by the Dbf4-dependent kinase.
Nat Struct Mol Biol. 2022 Jan;29(1):10-20. doi: 10.1038/s41594-021-00698-z. Epub 2021 Dec 28.
Nat Struct Mol Biol. 2022.
PMID: 34963704
Free PMC article.
Mechanism of replication origin melting nucleated by CMG helicase assembly.
Lewis JS, Gross MH, Sousa J, Henrikus SS, Greiwe JF, Nans A, Diffley JFX, Costa A.
Lewis JS, et al. Among authors: greiwe jf.
Nature. 2022 Jun;606(7916):1007-1014. doi: 10.1038/s41586-022-04829-4. Epub 2022 Jun 15.
Nature. 2022.
PMID: 35705812
Free PMC article.
Item in Clipboard
In silico reconstitution of DNA replication. Lessons from single-molecule imaging and cryo-tomography applied to single-particle cryo-EM.
Greiwe JF, Zanetti G, Miller TCR, Costa A.
Greiwe JF, et al.
Curr Opin Struct Biol. 2022 Feb;72:279-286. doi: 10.1016/j.sbi.2021.11.015. Epub 2022 Jan 10.
Curr Opin Struct Biol. 2022.
PMID: 35026552
Free PMC article.
Review.
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ReconSil: An electron microscopy toolbox to study helicase function at an origin of replication.
Pühringer T, Greiwe JF, Miller TCR, Costa A.
Pühringer T, et al. Among authors: greiwe jf.
Methods Enzymol. 2022;672:203-231. doi: 10.1016/bs.mie.2022.03.016. Epub 2022 Apr 22.
Methods Enzymol. 2022.
PMID: 35934476
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Mechanism of head-to-head MCM double-hexamer formation revealed by cryo-EM.
Miller TCR, Locke J, Greiwe JF, Diffley JFX, Costa A.
Miller TCR, et al. Among authors: greiwe jf.
Nature. 2019 Nov;575(7784):704-710. doi: 10.1038/s41586-019-1768-0. Epub 2019 Nov 20.
Nature. 2019.
PMID: 31748745
Free PMC article.
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TGFβ1 regulates HGF-induced cell migration and hepatocyte growth factor receptor MET expression via C-ets-1 and miR-128-3p in basal-like breast cancer.
Breunig C, Erdem N, Bott A, Greiwe JF, Reinz E, Bernhardt S, Giacomelli C, Wachter A, Kanthelhardt EJ, Beißbarth T, Vetter M, Wiemann S.
Breunig C, et al. Among authors: greiwe jf.
Mol Oncol. 2018 Sep;12(9):1447-1463. doi: 10.1002/1878-0261.12355. Epub 2018 Jul 30.
Mol Oncol. 2018.
PMID: 30004628
Free PMC article.
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Unwinding of a eukaryotic origin of replication visualized by cryo-EM.
Henrikus SS, Gross MH, Willhoft O, Pühringer T, Lewis JS, McClure AW, Greiwe JF, Palm G, Nans A, Diffley JFX, Costa A.
Henrikus SS, et al. Among authors: greiwe jf.
Nat Struct Mol Biol. 2024 May 17. doi: 10.1038/s41594-024-01280-z. Online ahead of print.
Nat Struct Mol Biol. 2024.
PMID: 38760633
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